Ritonavir

Name Ritonavir
Supplier Tocris Bioscience
Catalog 1955
Prices $99.00
Sizes 50 mg
Function Type Inhibitor
Cas Number 155213-67-5
Chemical Name 5-Thiazolylmethyl(3S,4S,6S,9S)-4-hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoate
Formula C37H48N6O5S2
Molecular Weight 720.94
Purity >98 %
Description HIV-1 and HIV-2 protease inhibitor (EC 50 values are 0.022-0.13 and 0.16 μ M, respectively). Blocks the metabolism of protease inhibitors by liver enzyme cytochrome P450-3A4 (CYP3A4). Orally bioavailable.
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Product References

Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- - Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)-

Luo W, Yu QS, Kulkarni SS, Parrish DA, Holloway HW, Tweedie D, Shafferman A, Lahiri DK, Brossi A, Greig NH. J Med Chem. 2006 Apr 6;49(7):2174-85.

The kinetics of inhibition of human acetylcholinesterase and - The kinetics of inhibition of human acetylcholinesterase and

Groner E, Ashani Y, Schorer-Apelbaum D, Sterling J, Herzig Y, Weinstock M. Mol Pharmacol. 2007 Jun;71(6):1610-7. Epub 2007 Mar 8.

Rivastigmine lowers Abeta and increases sAPPalpha levels, which parallel elevated - Rivastigmine lowers Abeta and increases sAPPalpha levels, which parallel elevated

Bailey JA, Ray B, Greig NH, Lahiri DK. PLoS One. 2011;6(7):e21954.

New acetylcholinesterase inhibitors for Alzheimer's disease. - New acetylcholinesterase inhibitors for Alzheimer's disease.

Mehta M, Adem A, Sabbagh M. Int J Alzheimers Dis. 2012;2012:728983.