RJR 2403 oxalate

• Supplier: Tocris Bioscience
• Catalog: 5136
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 220662-95-3
• Chemical Name: (E)-N-Methyl-4-(3-pyridinyl)-3-buten-1-amineoxalate
• Formula: C10H14N2.C2H2O4
• Molecular Weight: 252.27
• Purity: >99 %
• Description: A neuronal nicotinic receptor agonist, showing high selectivity for the α 4 β 2 subtype (K i values are 26 and 36000 nM for α 4 β 2 and α 7 receptors respectively). Active in vivo .

Product References

RJR-2403: a nicotinic agonist with CNS selectivity I. In vitro characterization. - RJR-2403: a nicotinic agonist with CNS selectivity I. In vitro characterization.

Bencherif M, Lovette ME, Fowler KW, Arrington S, Reeves L, Caldwell WS, Lippiello PM. J Pharmacol Exp Ther. 1996 Dec;279(3):1413-21.

RJR-2403: a nicotinic agonist with CNS selectivity II. In vivo characterization. - RJR-2403: a nicotinic agonist with CNS selectivity II. In vivo characterization.

Lippiello PM, Bencherif M, Gray JA, Peters S, Grigoryan G, Hodges H, Collins AC. J Pharmacol Exp Ther. 1996 Dec;279(3):1422-9.

Antinociceptive and pharmacological effects of metanicotine, a selective - Antinociceptive and pharmacological effects of metanicotine, a selective

Damaj MI, Glassco W, Aceto MD, Martin BR. J Pharmacol Exp Ther. 1999 Oct;291(1):390-8.