Name | RMM 46 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 3393 |
Prices | $179.00, $755.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 1307896-46-3 |
Chemical Name | 2-Cyano-N-(2-hydroxy-1,1-dimethylethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]-2-propenamide |
Formula | C24H26N4O5 |
Molecular Weight | 450.5 |
Purity | >98 % |
Description | MSK/RSK family kinase inhibitor. Exhibits selectivity for RSK2 over NEK2 and PLK1 (IC 50 s are 12, 530 and 2200 nM, respectively). Inhibits MSK1, MSK2, RSK2 and RSK3 in cellular assays. Reduces CREB phosphorylation in HeLa cells. |
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