RMM 46

Name RMM 46
Supplier Tocris Bioscience
Catalog 3393
Prices $179.00, $755.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 1307896-46-3
Chemical Name 2-Cyano-N-(2-hydroxy-1,1-dimethylethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]-2-propenamide
Formula C24H26N4O5
Molecular Weight 450.5
Purity >98 %
Description MSK/RSK family kinase inhibitor. Exhibits selectivity for RSK2 over NEK2 and PLK1 (IC 50 s are 12, 530 and 2200 nM, respectively). Inhibits MSK1, MSK2, RSK2 and RSK3 in cellular assays. Reduces CREB phosphorylation in HeLa cells.
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