| Name | RN 1747 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3746 |
| Prices | $129.00, $535.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 1024448-59-6 |
| Chemical Name | 1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine |
| Formula | C17H18ClN3O4S |
| Molecular Weight | 395.87 |
| Description | Selective TRPV4 agonist (EC 50 values are 0.77, 4.0 and 4.1 μ M for hTRPV4, mTRPV4 and rTRPV4 respectively). Displays selectivity over other TRP channels (EC 50 values are 0.77, >30, >30 and >100 μ M for TRPV4, TRPM8, TRPV3 and TRPV1 receptors respectively). Also antagonizes TRPM8 at relevant concentrations (IC 50 = 4 μ M). |
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