Ro 32-3555

Name Ro 32-3555
Supplier Tocris Bioscience
Catalog 1587
Prices $259.00
Sizes 10 mg
Function Type Inhibitor
Cas Number 190648-49-8
Chemical Name (αR,βR)-β-(Cyclopentylmethyl)-N-hydroxy-γ-oxo-α-[(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-1-piperidinebutanamide
Formula C22H36N4O5
Molecular Weight 436.55
Purity >97 %
Description Potent, collagenase-selective MMP inhibitor (K i values are 3.0, 3.4, 4.4, 59, 154 and 527 nM for MMP-1, MMP-13, MMP-8, MMP-9, MMP-2 and MMP-3 respectively). Inhibits cartilage breakdown in vitro and in vivo and displays antiarthritic activity. Orally active.
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