Name | Ro 32-3555 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 1587 |
Prices | $259.00 |
Sizes | 10 mg |
Function Type | Inhibitor |
Cas Number | 190648-49-8 |
Chemical Name | (αR,βR)-β-(Cyclopentylmethyl)-N-hydroxy-γ-oxo-α-[(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-1-piperidinebutanamide |
Formula | C22H36N4O5 |
Molecular Weight | 436.55 |
Purity | >97 % |
Description | Potent, collagenase-selective MMP inhibitor (K i values are 3.0, 3.4, 4.4, 59, 154 and 527 nM for MMP-1, MMP-13, MMP-8, MMP-9, MMP-2 and MMP-3 respectively). Inhibits cartilage breakdown in vitro and in vivo and displays antiarthritic activity. Orally active. |
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