Ro 51

Name Ro 51
Supplier Tocris Bioscience
Catalog 5389
Prices $199.00, $825.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 1050670-85-3
Chemical Name 2-[[4-Amino-5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinyl]amino]-1,3-propanediol
Formula C17H23IN4O4
Molecular Weight 474.29
Purity >98 %
Description Potent, dual P2X 3 and P2X 2/3 antagonist (IC 50 values are 2 and 5 nM for rP2X 3 and hP2X 2/3 respectively). Selective for P2X 3 and P2X 2/3 over other P2X receptors (IC 50 values are > 10 μ M for P2X 1 , P2X 2 , P2X 4 , P2X 5 , and P2X 7 ). Cell permeable.
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