( S )-(+)-Rolipram

Name ( S )-(+)-Rolipram
Supplier Tocris Bioscience
Catalog 1349
Prices $199.00, $825.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 85416-73-5
Chemical Name (4S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
Formula C16H21NO3
Molecular Weight 275.35
Purity >99 %
Description Less active enantiomer of the PDE4 inhibitor rolipram (Cat. No. 0905). ( R )-(-)-Rolipram (Cat. No. 1349) also available.
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Product References

Stereospecific binding of the antidepressant rolipram to brain protein - Stereospecific binding of the antidepressant rolipram to brain protein

Schneider HH, Schmiechen R, Brezinski M, Seidler J. Eur J Pharmacol. 1986 Aug 7;127(1-2):105-15.

Human phosphodiesterase 4A: characterization of full-length and truncated enzymes - Human phosphodiesterase 4A: characterization of full-length and truncated enzymes

Owens RJ, Catterall C, Batty D, Jappy J, Russell A, Smith B, O'Connell J, Perry MJ. Biochem J. 1997 Aug 15;326 ( Pt 1):53-60.

Inhibitory effects of rolipram on partially purified phosphodiesterase 4 from rat - Inhibitory effects of rolipram on partially purified phosphodiesterase 4 from rat

Ohsawa F, Yamauchi M, Nagaso H, Murakami S, Baba J, Sawa A. Jpn J Pharmacol. 1998 Jun;77(2):147-54.