| Name | Rosiglitazone |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5168 |
| Prices | $69.00, $295.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 122320-73-4 |
| Chemical Name | 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Formula | C18H19N3O3S |
| Molecular Weight | 357.43 |
| Purity | >99 % |
| Description | Potent and selective PPAR γ agonist (EC 50 = 60 nM); exhibits no activity at PPAR α and PPAR β . Promotes differentiation of pluripotent C3H10T1/2 stem cells into adipocytes. Exhibits antihyperglycemic activity in diabetic ob/ob mouse model. Antidiabetic agent. |
| Supplier Page | Shop |
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. J Biol Chem. 1995 Jun 2;270(22):12953-6.
Willson TM, Cobb JE, Cowan DJ, Wiethe RW, Correa ID, Prakash SR, Beck KD, Moore LB, Kliewer SA, Lehmann JM. J Med Chem. 1996 Feb 2;39(3):665-8.