Rostafuroxin

• Supplier: Tocris Bioscience
• Catalog: 0630
• Prices: $195.00, $805.00
• Sizes: 10 mg, 50 mg
• Function Type: Modulator
• Cas Number: 156722-18-8
• Chemical Name: 3β,5β,14β)-21,23-Epoxy-24-norchola-20,22-diene-3,14,17-triol
• Formula: C23H34O4
• Molecular Weight: 374.51
• Purity: >98 %
• Description: Na + /K + ATPase modulator. Normalizes renal Na + /K + ATPase pump function in mutant adducin- and endogenous ouabain-dependent forms of hypertension. Reduces blood pressure in Milan hypersensitive rats. Controls mania-like behaviors in Myshkin mice having a Na + /K + ATPase α 3 subunit mutation.

Product References

Organ hypertrophic signaling within caveolae membrane subdomains triggered by - Organ hypertrophic signaling within caveolae membrane subdomains triggered by

Ferrandi M, Molinari I, Barassi P, Minotti E, Bianchi G, Ferrari P. J Biol Chem. 2004 Aug 6;279(32):33306-14. Epub 2004 May 25.

Rostafuroxin: an ouabain antagonist that corrects renal and vascular Na+-K+- - Rostafuroxin: an ouabain antagonist that corrects renal and vascular Na+-K+-

Ferrari P, Ferrandi M, Valentini G, Bianchi G. Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R529-35.

Rostafuroxin: an ouabain-inhibitor counteracting specific forms of hypertension. - Rostafuroxin: an ouabain-inhibitor counteracting specific forms of hypertension.

Ferrari P. Biochim Biophys Acta. 2010 Dec;1802(12):1254-8. doi: