Rp-8-pCPT-cGMPS sodium

• Supplier: Tocris Bioscience
• Catalog: 1635
• Prices: $255.00
• Sizes: 1 mg
• Function Type: Inhibitor
• Cas Number: 208445-07-2
• Chemical Name: 8-[(4-Chlorophenyl)thio]-guanosine-cyclic3',5'-[hydrogen[P(R)]-phosphorothioate]sodium
• Formula: C16H14ClN5NaO6PS2
• Molecular Weight: 525.86
• Purity: >99 %
• Description: PKG inhibitor (K i values are 0.45, 0.5 and 0.7 μ M for PKGI β , PKGI α and PKGII respectively). Exhibits selectivity for PKG over PKA and Epac-1. Reduces LTP in hippocampal slices in vitro .

Product References

The type II isoform of cGMP-dependent protein kinase is dimeric and possesses - The type II isoform of cGMP-dependent protein kinase is dimeric and possesses

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Cyclic nucleotide analogs as probes of signaling pathways. - Cyclic nucleotide analogs as probes of signaling pathways.

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Network compensation of cyclic GMP-dependent protein kinase II knockout in the - Network compensation of cyclic GMP-dependent protein kinase II knockout in the

Kim S, Titcombe RF, Zhang H, Khatri L, Girma HK, Hofmann F, Arancio O, Ziff EB. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3122-7. doi: