Name | RU 58668 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 1672 |
Prices | $269.00 |
Sizes | 10 mg |
Cas Number | 151555-47-4 |
Chemical Name | (11β,17β)-11-[4-[[5-[(4,4,5,5,5-Pentafluoropentyl)sulfonyl]pentyl]oxy]phenylestra-1,3,5,(10)-triene-3,17-diol |
Formula | C34H43F5O5S |
Molecular Weight | 658.76 |
Purity | >95 % |
Description | Pure antiestrogen that downregulates estrogen receptor expression (IC 50 = 0.04 nM). Displays potent antiproliferative activity in vitro (IC 50 = 0.035 - 0.09 nM in MCF-7 cells) and causes long term regression of tamoxifen-resistant MCF-7 xenografts in vivo . |
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