Rufinamide

• Supplier: Tocris Bioscience
• Catalog: 3855
• Prices: $159.00, $665.00
• Sizes: 10 mg, 50 mg
• Cas Number: 106308-44-5
• Chemical Name: 1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide
• Formula: C10H8F2N4O
• Molecular Weight: 238.19
• Purity: >99 %
• Description: Board spectrum anticonvulsant. Prolongs the inactivation of sodium channels and limits the frequency of action potential firing in cultured and acutely isolated neurons. Displays anticonvulsive activity in a range of animal seizure models.

Product References

Diverse mechanisms of antiepileptic drugs in the development pipeline. - Diverse mechanisms of antiepileptic drugs in the development pipeline.

Rogawski MA. Epilepsy Res. 2006 Jun;69(3):273-94. Epub 2006 Apr 18.

Rufinamide. - Rufinamide.

Arroyo S. Neurotherapeutics. 2007 Jan;4(1):155-62.

The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models. - The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models.

White HS, Franklin MR, Kupferberg HJ, Schmutz M, Stables JP, Wolf HH. Epilepsia. 2008 Jul;49(7):1213-20.