Ruthenium Red

Name Ruthenium Red
Supplier Tocris Bioscience
Catalog 4886
Prices $95.00
Sizes 100 mg
Cas Number 11103-72-3
Chemical Name Ammoniatedrutheniumoxychloride
Formula H42N14O2Ru3Cl6
Molecular Weight 786.35
Description Blocks Ca 2+ uptake and release from mitochondria, and Ca 2+ release from ryanodine-sensitive intracellular stores. Also blocks cell membrane-located capsaicin-activated cation channels (IC 50 = 14 nM) and voltage-sensitive Ca 2+ channels to inhibit neurotransmitter release.
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Product References

Pathway for uncoupler-induced calcium efflux in rat liver mitochondria: - Pathway for uncoupler-induced calcium efflux in rat liver mitochondria:

Bernardi P, Paradisi V, Pozzan T, Azzone GF. Biochemistry. 1984 Apr 10;23(8):1645-51.

Ruthenium red as a capsaicin antagonist. - Ruthenium red as a capsaicin antagonist.

Amann R, Maggi CA. Life Sci. 1991;49(12):849-56.

Vanilloid (Capsaicin) receptors and mechanisms. - Vanilloid (Capsaicin) receptors and mechanisms.

Szallasi A, Blumberg PM. Pharmacol Rev. 1999 Jun;51(2):159-212.

Ruthenium red modifies the cardiac and skeletal muscle Ca(2+) release channels - Ruthenium red modifies the cardiac and skeletal muscle Ca(2+) release channels

Xu L, Tripathy A, Pasek DA, Meissner G. J Biol Chem. 1999 Nov 12;274(46):32680-91.