RX 821002 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2999
• Prices: $69.00, $249.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 109544-45-8
• Chemical Name: 2-(2,3-Dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazolehydrochloride
• Formula: C12H14N2O3.HCl
• Molecular Weight: 270.72
• Purity: >99 %
• Description: Potent, selective α 2 -adrenoceptor antagonist with very low affinity for imidazoline sites. Displays selectivity for the α 2D over the α 2A subtypes (pK d values are 9.7 and 8.2 respectively).

Product References

Characterization of [3H]RX821002 binding to alpha-2 adrenergic receptor subtypes. - Characterization of [3H]RX821002 binding to alpha-2 adrenergic receptor subtypes.

O'Rourke MF, Blaxall HS, Iversen LJ, Bylund DB. J Pharmacol Exp Ther. 1994 Mar;268(3):1362-7.

Does [3H]2-methoxy-idazoxan (RX 821002) detect more alpha-2-adrenoceptor agonist - Does [3H]2-methoxy-idazoxan (RX 821002) detect more alpha-2-adrenoceptor agonist

Erdbrugger W, Raulf M, Otto T, Michel MC. J Pharmacol Exp Ther. 1995 Jun;273(3):1287-94.

Antagonists that differentiate between alpha 2A-and alpha 2D-adrenoceptors. - Antagonists that differentiate between alpha 2A-and alpha 2D-adrenoceptors.

Trendelenburg AU, Wahl CA, Starke K. Naunyn Schmiedebergs Arch Pharmacol. 1996 Feb;353(3):245-9.