Ryanodine

• Supplier: Tocris Bioscience
• Catalog: 1324
• Prices: $189.00
• Sizes: 1 mg
• Function Type: Inhibitor
• Cas Number: 15662-33-6
• Chemical Name: 1H-Pyrrole-2-carboxylicacid,(3S,4R,4aR,6S,7S,8R,8aS,8bR,9S,9aS)-dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethyl-7-(1-methylethyl)-6,9-methanobenzo[1,2]pentaleno[1,6-bc]furan-8-ylester
• Formula: C25H35NO9
• Molecular Weight: 493.55
• Purity: >98 %
• Description: Potent inhibitor of Ca 2+ release from sarcoplasmic reticulum (IC 50 values are 10 and 2.8 nM in skeletal and cardiac muscle respectively).

Product References

Ryanodine: a modifier of sarcoplasmic reticulum calcium release in striated - Ryanodine: a modifier of sarcoplasmic reticulum calcium release in striated

Sutko JL, Ito K, Kenyon JL. Fed Proc. 1985 Dec;44(15):2984-8.

Conformation state of the ryanodine receptor and functional effects of ryanodine - Conformation state of the ryanodine receptor and functional effects of ryanodine

Bianchi CP. Biochem Pharmacol. 1997 Apr 4;53(7):909-12.

The pharmacology of ryanodine and related compounds. - The pharmacology of ryanodine and related compounds.

Sutko JL, Airey JA, Welch W, Ruest L. Pharmacol Rev. 1997 Mar;49(1):53-98.