S 18986

• Supplier: Tocris Bioscience
• Catalog: 5568
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Modulator
• Cas Number: 175340-20-2
• Chemical Name: (3aS)-2,3,3a,4-Tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine-5,5-dioxide
• Formula: C10H12N2O2S
• Molecular Weight: 224.28
• Purity: >98 %
• Description: Positive allosteric modulator of AMPA receptors. Exhibits cognitive enhancing properties in rodent behavioral models. Brain penetrant.

Product References

(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) - (S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1)

Lockhart B, Iop F, Closier M, Lestage P. Eur J Pharmacol. 2000 Aug 4;401(2):145-53.

Neuropharmacokinetics of a new alpha-amino-3-hydroxy-5-methyl-4-isoxazole - Neuropharmacokinetics of a new alpha-amino-3-hydroxy-5-methyl-4-isoxazole

Bourasset F, Bernard K, Munoz C, Genissel P, Scherrmann JM. Drug Metab Dispos. 2005 Aug;33(8):1137-43. Epub 2005 Apr 28.