S 25585

Name S 25585
Supplier Tocris Bioscience
Catalog 3518
Prices $199.00, $825.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 263849-50-9
Chemical Name 1-Benzoyl-2-[[trans-4-[[[[2-nitro-4-(trifluoromethyl)phenyl]sulfonyl]amino]methyl]cyclohexyl]carbonyl]hydrazine
Formula C22H23F3N4O6S
Molecular Weight 528.5
Purity >98 %
Description Potent neuropeptide Y (NPY) Y 5 receptor antagonist (IC 50 values are 5.4, > 1000, > 10 000 and > 10 000 nM at Y 5 , Y 1 , Y 2 and Y 4 receptors respectively) that displays no affinity for a wide range of other receptors. Does not produce a conditioned taste aversion, suppress sodium appetite or cause pica in rats. Significantly inhibits NPY-induced feeding but not through blockade of Y 5 receptors.
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