Name | S 25585 |
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Supplier | Tocris Bioscience |
Catalog | 3518 |
Prices | $199.00, $825.00 |
Sizes | 10 mg, 50 mg |
Function Type | Antagonist |
Cas Number | 263849-50-9 |
Chemical Name | 1-Benzoyl-2-[[trans-4-[[[[2-nitro-4-(trifluoromethyl)phenyl]sulfonyl]amino]methyl]cyclohexyl]carbonyl]hydrazine |
Formula | C22H23F3N4O6S |
Molecular Weight | 528.5 |
Purity | >98 % |
Description | Potent neuropeptide Y (NPY) Y 5 receptor antagonist (IC 50 values are 5.4, > 1000, > 10 000 and > 10 000 nM at Y 5 , Y 1 , Y 2 and Y 4 receptors respectively) that displays no affinity for a wide range of other receptors. Does not produce a conditioned taste aversion, suppress sodium appetite or cause pica in rats. Significantly inhibits NPY-induced feeding but not through blockade of Y 5 receptors. |
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