| Name | S26948 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3404 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 353280-43-0 |
| Chemical Name | [[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioicaciddimethylester |
| Formula | C28H25NO7S |
| Molecular Weight | 519.57 |
| Purity | >99 % |
| Description | Selective PPAR γ agonist (EC 50 = 8.83 nM). Drives normal adipocyte differentiation and exhibits a lipid-lowering effect; reduces atherosclerosis in E2-KI mice. Displays antidiabetic properties and improves hepatic insulin sensitivity in intralipid-infusion (IL) rats. |
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Carmona MC, Louche K, Lefebvre B, Pilon A, Hennuyer N, Audinot-Bouchez V, Fievet C, Torpier G, Formstecher P, Renard P, Lefebvre P, Dacquet C, Staels B, Casteilla L, Penicaud L. Diabetes. 2007 Nov;56(11):2797-808. Epub 2007 Aug 17.
Sohn KA, Cruciani-Guglielmacci C, Kassis N, Clement L, Ouali F, Cauzac M, Lebegue N, Berthelot P, Caignard DH, Pegorier JP, Renard P, Dacquet C, Ktorza A, Magnan C. Eur J Pharmacol. 2009 Apr 17;608(1-3):104-11.