SANT-1

Name SANT-1
Supplier Tocris Bioscience
Catalog 2302
Prices $175.00, $709.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 304909-07-7
Chemical Name N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine
Formula C23H27N5
Molecular Weight 373.5
Purity >99 %
Description Potent, cell-permeable inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (K D = 1.2 nM). Inhibits smoothened agonist effects with an IC 50 of 20 nM (in Shh-LIGHT2 cells).
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