Name | SANT-1 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 2302 |
Prices | $175.00, $709.00 |
Sizes | 10 mg, 50 mg |
Function Type | Antagonist |
Cas Number | 304909-07-7 |
Chemical Name | N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine |
Formula | C23H27N5 |
Molecular Weight | 373.5 |
Purity | >99 % |
Description | Potent, cell-permeable inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (K D = 1.2 nM). Inhibits smoothened agonist effects with an IC 50 of 20 nM (in Shh-LIGHT2 cells). |
Supplier Page | Shop |