| Name | SANT-2 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1974 |
| Prices | $185.00, $755.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 329196-48-7 |
| Chemical Name | N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide |
| Formula | C26H26ClN3O4 |
| Molecular Weight | 479.96 |
| Purity | >98 % |
| Description | Inhibitor of Sonic hedgehog (Shh) signaling; antagonizes smoothened receptor activity (K D = 12 nM). Displays allosteric binding characteristics similar to SANT-1 (Cat. No. 1974). Displaces smo-[ 3 H]SAG-1.3 and -[ 3 H]Cyclopamine binding (K i values are 7.8 nM and 8.4 nM respectively). |
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