SAR 216471 hydrochloride

Name SAR 216471 hydrochloride
Supplier Tocris Bioscience
Catalog 4418
Prices $289.00
Sizes 10 mg
Function Type Antagonist
Cas Number 1279829-64-9
Chemical Name 5-Chloro-N-[6-[5-methyl-4-(1-oxobutyl)-1H-pyrazol-1-yl]-3-pyridazinyl]-1-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-1H-indole-3-carboxamidehydrochloride
Formula C28H31ClN8O3.HCl
Molecular Weight 599.51
Purity >98 %
Description Potent P2Y 12 antagonist (IC 50 = 17 nM). Displays antiplatelet and antithrombotic activity in vivo . Orally available.
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Product References

Comparison of responses to sarafotoxins 6a and 6c in pulmonary and systemic - Comparison of responses to sarafotoxins 6a and 6c in pulmonary and systemic

Minkes RK, Bellan JA, Higuera TR, Kadowitz PJ. Am J Physiol. 1992 Mar;262(3 Pt 2):H852-61.

Differences between endothelin receptors mediating contraction of guinea-pig - Differences between endothelin receptors mediating contraction of guinea-pig

Schoeffter P, Randriantsoa A. Eur J Pharmacol. 1993 Nov 9;249(2):199-206.

Endothelin-induced nociception in mice: mediation by ETA and ETB receptors. - Endothelin-induced nociception in mice: mediation by ETA and ETB receptors.

Raffa RB, Schupsky JJ, Jacoby HI. J Pharmacol Exp Ther. 1996 Feb;276(2):647-51.