SB 200646 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2736
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 143797-62-0
• Chemical Name: N-(1-Methyl-1H-indol-5-yl)-N'-3-pyridinylurea
• Formula: C15H14N4O.HCl
• Molecular Weight: 302.76
• Purity: >98 %
• Description: 5-HT 2C/2B receptor antagonist, selective over 5-HT 1A . Affinities are 7.4 (pA 2 ), 6.9 (pK i ) and 5.2 (pK i ) for 5-HT 2B , 2C and 2A respectively. Orally active in vivo .

Product References

N-(1-methyl-5-indolyl)-N'-(3-pyridyl)urea hydrochloride: the first selective - N-(1-methyl-5-indolyl)-N'-(3-pyridyl)urea hydrochloride: the first selective

Forbes IT, Kennett GA, Gadre A, Ham P, Hayward CJ, Martin RT, Thompson M, Wood MD, Baxter GS, Glen A, et al.. J Med Chem. 1993 Apr 16;36(8):1104-7.

In vivo properties of SB 200646A, a 5-HT2C/2B receptor antagonist. - In vivo properties of SB 200646A, a 5-HT2C/2B receptor antagonist.

Kennett GA, Wood MD, Glen A, Grewal S, Forbes I, Gadre A, Blackburn TP. Br J Pharmacol. 1994 Mar;111(3):797-802.

Effect of SB 200646A, a 5-HT2C/5-HT2B receptor antagonist, in two conflict models - Effect of SB 200646A, a 5-HT2C/5-HT2B receptor antagonist, in two conflict models

Kennett GA, Bailey F, Piper DC, Blackburn TP. Psychopharmacology (Berl). 1995 Mar;118(2):178-82.