SB 216641 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 1374
• Prices: $209.00, $879.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 193611-67-5
• Chemical Name: N-[3-[3-(Dimethylamino)ethoxy]-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamidehydrochloride
• Formula: C28H30N4O4.HCl
• Molecular Weight: 523.03
• Purity: >98 %
• Description: A selective h5-HT 1B antagonist with approximately 25-fold selectivity over h5-HT 1D and little or no affinity for a range of other receptor types.

Product References

Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig. - Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig.

Hagan JJ, Slade PD, Gaster L, Jeffrey P, Hatcher JP, Middlemiss DN. Eur J Pharmacol. 1997 Jul 23;331(2-3):169-74.

[The regeneration of peripheral nerves. Anatomo-pathological considerations]. - [The regeneration of peripheral nerves. Anatomo-pathological considerations].

Reznik M. Acta Orthop Belg. 1977 Mar-Apr;43(2):145-50.

Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands - Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands

Schlicker E, Fink K, Molderings GJ, Price GW, Duckworth M, Gaster L, Middlemiss DN, Zentner J, Likungu J, Gothert M. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):321-7.