| Name | SB 277011A dihydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3368 |
| Prices | $175.00, $709.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 1226917-67-4 |
| Chemical Name | N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamidedihydrochloride |
| Formula | C28H30N4O.2HCl |
| Molecular Weight | 511.49 |
| Purity | >98 % |
| Description | Selective dopamine D 3 receptor antagonist (pK i values are 8.0, 6.0, 5.0 and <5.2 for D 3 , D 2 , 5-HT 1D and 5-HT 1B respectively). Brain penetrant. |
| Supplier Page | Shop |
Reavill C, Taylor SG, Wood MD, Ashmeade T, Austin NE, Avenell KY, Boyfield I, Branch CL, Cilia J, Coldwell MC, Hadley MS, Hunter AJ, Jeffrey P, Jewitt F, Johnson CN, Jones DN, Medhurst AD, Middlemiss DN, Nash DJ, Riley GJ, Routledge C, Stemp G, Thewlis KM, Trail B, Vong AK, Hagan JJ. J Pharmacol Exp Ther. 2000 Sep;294(3):1154-65.
Stemp G, Ashmeade T, Branch CL, Hadley MS, Hunter AJ, Johnson CN, Nash DJ, Thewlis KM, Vong AK, Austin NE, Jeffrey P, Avenell KY, Boyfield I, Hagan JJ, Middlemiss DN, Reavill C, Riley GJ, Routledge C, Wood M. J Med Chem. 2000 May 4;43(9):1878-85.