| Name | SB 399885 hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1615 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 402713-81-9 |
| Chemical Name | N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamidehydrochloride |
| Formula | C18H21Cl2N3O4S.HCl |
| Molecular Weight | 482.81 |
| Purity | >99 % |
| Description | Potent, brain penetrant, orally active 5-HT 6 antagonist. Displays > 200-fold selectivity for 5-HT 6 over other 5-HT receptors (pK i values are 9.11, 8.81 and 9.02 for human recombinant, native rat and native human 5-HT 6 receptors respectively). |
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Wesolowska A, Nikiforuk A. Neuropharmacology. 2007 Apr;52(5):1274-83. Epub 2007 Jan 20.
Foley AG, Hirst WD, Gallagher HC, Barry C, Hagan JJ, Upton N, Walsh FS, Hunter AJ, Regan CM. Neuropharmacology. 2008 Jun;54(8):1166-74.