| Name | SB 674042 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3571 |
| Prices | $289.00, $1,185.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 483313-22-0 |
| Chemical Name | [5-(2-Fluorophenyl)-2-methyl-4-thiazolyl][2(S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl-1-pyrrolidinyl]methanone |
| Formula | C24H21FN4O2S |
| Molecular Weight | 448.51 |
| Description | Potent and selective non-peptide orexin OX 1 receptor antagonist (K d = 3.76 nM). Exhibits 100-fold selectivity for OX 1 over OX 2 receptors. Has no effect at serotonergic, dopaminergic, adrenergic or purinergic receptors. Inhibits orexin 1-induced Ca 2+ mobilization in CHO-DG44 cells stably transfected with the OX 1 receptor. |
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