| Name | SB 706504 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4667 |
| Prices | $235.00, $965.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 911110-38-8 |
| Chemical Name | N-Cyano-N'-[2-[[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7,8-dihydro-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]ethyl]guanidine |
| Formula | C24H19F3N8O |
| Molecular Weight | 492.46 |
| Purity | >98 % |
| Description | p38 MAPK inhibitor. Inhibits LPS-induced transcription of a range of chemokines and cytokines in chronic obstructive pulmonary disease (COPD) monocyte derived macrophages (MDMs). Also inhibits LPS-induced protein expression of IL-6, IL-10, TNF α and γ -inducible protein 10 in COPD MDMs. Effects on suppression of LPS-induced gene and protein expression are enhanced in combination with dexamethasone (Cat. No. 1126). |
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