| Name | SB 772077B dihydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4630 |
| Prices | $255.00, $1,045.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 607373-46-6 |
| Chemical Name | (3S)-1-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]carbonyl]-3-pyrrolidinaminedihydrochloride |
| Formula | C15H18N8O2.2HCl |
| Molecular Weight | 415.28 |
| Purity | >99 % |
| Description | Potent Rho-kinase (ROCK) inhibitor (IC 50 value of approximately 5.6 nM at recombinant human ROCK1 and 2). Decreases pulmonary and systemic arterial blood pressures and increases cardiac output. Exhibits vasodilator activity that is more potent than Y-27632 (Cat.No 1254) or Fasudil (Cat.No. 0541). |
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