Name | SBHA |
---|---|
Supplier | Tocris Bioscience |
Catalog | 4292 |
Prices | $59.00 |
Sizes | 50 mg |
Function Type | Inhibitor |
Cas Number | 38937-66-5 |
Chemical Name | N,N'-Dihydroxyoctanediamide |
Formula | C8H16N2O4 |
Molecular Weight | 204.22 |
Description | Histone deacetylase (HDAC) inhibitor (ID 50 values are 0.25 and 0.3 μ M for HDAC1 and HDAC3 respectively). Potentiates the cytostatic effects of 5-Fluorouracil (Cat. No. 3257) in colorectal cancer cells. |
Supplier Page | Shop |
Richon VM, Emiliani S, Verdin E, Webb Y, Breslow R, Rifkind RA, Marks PA. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3003-7.
Brinkmann H, Dahler AL, Popa C, Serewko MM, Parsons PG, Gabrielli BG, Burgess AJ, Saunders NA. J Biol Chem. 2001 Jun 22;276(25):22491-9. Epub 2001 Apr 13.
Zhang XD, Gillespie SK, Borrow JM, Hersey P. Mol Cancer Ther. 2004 Apr;3(4):425-35.