SCH 202676 hydrobromide

• Supplier: Tocris Bioscience
• Catalog: 0433
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 265980-25-4
• Chemical Name: N-(2,3-Diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)methanaminehydrobromide
• Formula: C15H13N3S.HBr
• Molecular Weight: 348.26
• Purity: >99 %
• Description: Sulphydryl-reactive compound that inhibits agonist and antagonist binding to G-protein-coupled receptors. Inhibits a variety of GPCRs including adenosine, opioid, muscarinic, adrenergic and dopaminergic receptors (IC 50 values are 0.1-1.8 μ M).

Product References

SCH-202676: An allosteric modulator of both agonist and antagonist binding to G - SCH-202676: An allosteric modulator of both agonist and antagonist binding to G

Fawzi AB, Macdonald D, Benbow LL, Smith-Torhan A, Zhang H, Weig BC, Ho G, Tulshian D, Linder ME, Graziano MP. Mol Pharmacol. 2001 Jan;59(1):30-7.

Effects of the allosteric modulator SCH-202676 on adenosine and P2Y receptors. - Effects of the allosteric modulator SCH-202676 on adenosine and P2Y receptors.

Gao ZG, Gross AS, Jacobson KA. Life Sci. 2004 May 7;74(25):3173-80.

The 'allosteric modulator' SCH-202676 disrupts G protein-coupled receptor - The 'allosteric modulator' SCH-202676 disrupts G protein-coupled receptor

Lewandowicz AM, Vepsalainen J, Laitinen JT. Br J Pharmacol. 2006 Feb;147(4):422-9.