SCH 39166 hydrobromide

• Supplier: Tocris Bioscience
• Catalog: 1690
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 1227675-51-5
• Chemical Name: (6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-olhydrobromide
• Formula: C19H20ClNO.HBr
• Molecular Weight: 394.73
• Purity: >99 %
• Description: High affinity dopamine D 1 /D 5 receptor antagonist; displays K i values of 1.2, 2, 980, 5520, 80 and 731 nM for binding to D 1 , D 5 , D 2 , D 4 , 5-HT and α 2a receptors, respectively.

Product References

In vivo binding of SCH 39166: a D-1 selective antagonist. - In vivo binding of SCH 39166: a D-1 selective antagonist.

McQuade RD, Duffy RA, Coffin VL, Chipkin RE, Barnett A. J Pharmacol Exp Ther. 1991 Apr;257(1):42-9.

A comparison of the effects of the D1 receptor antagonists SCH 23390 and SCH - A comparison of the effects of the D1 receptor antagonists SCH 23390 and SCH

Terry P, Katz JL. Psychopharmacology (Berl). 1994 Jan;113(3-4):328-33.

Dopamine D1/D5 receptor antagonists with improved pharmacokinetics: design, - Dopamine D1/D5 receptor antagonists with improved pharmacokinetics: design,

Wu WL, Burnett DA, Spring R, Greenlee WJ, Smith M, Favreau L, Fawzi A, Zhang H, Lachowicz JE. J Med Chem. 2005 Feb 10;48(3):680-93.