Name | SDZ 220-581 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 1251 |
Prices | $199.00, $825.00 |
Sizes | 10 mg, 50 mg |
Function Type | Antagonist |
Cas Number | 174575-17-8 |
Chemical Name | (S)-α-Amino-2'-chloro-5-(phosphonomethyl)[1,1'-biphenyl]-3-propanoicacid |
Formula | C16H17ClNO5P |
Molecular Weight | 369.74 |
Purity | >98 % |
Description | Competitive NMDA receptor antagonist (pK i = 7.7). Centrally active following oral administration (ED 50 < 3.2 mg/kg for protection against MES-induced seizures). |
Supplier Page | Shop |
Urwyler S, Laurie D, Lowe DA, Meier CL, Muller W. Neuropharmacology. 1996 Jun;35(6):643-54.
Urwyler S, Campbell E, Fricker G, Jenner P, Lemaire M, McAllister KH, Neijt HC, Park CK, Perkins M, Rudin M, Sauter A, Smith L, Wiederhold KH, Muller W. Neuropharmacology. 1996 Jun;35(6):655-69.
Bakshi VP, Tricklebank M, Neijt HC, Lehmann-Masten V, Geyer MA. J Pharmacol Exp Ther. 1999 Feb;288(2):643-52.