Name | Senexin A |
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Supplier | Tocris Bioscience |
Catalog | 4699 |
Prices | $209.00 |
Sizes | 10 mg |
Function Type | Inhibitor |
Chemical Name | 4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitrilehydrochloride |
Formula | C17H14N4.HCl |
Molecular Weight | 310.78 |
Purity | >98 % |
Description | Cyclin-dependent kinase 8 (cdk8) inhibitor (IC 50 = 280 nM). Also binds to cdk19 in an ATP-competitive manner. Inhibits p21-induced transcription. Reverses doxorubicin -induced tumor-promoting paracrine activities in vivo . |
Supplier Page | Shop |