Senexin A

Name Senexin A
Supplier Tocris Bioscience
Catalog 4699
Prices $209.00
Sizes 10 mg
Function Type Inhibitor
Chemical Name 4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitrilehydrochloride
Formula C17H14N4.HCl
Molecular Weight 310.78
Purity >98 %
Description Cyclin-dependent kinase 8 (cdk8) inhibitor (IC 50 = 280 nM). Also binds to cdk19 in an ATP-competitive manner. Inhibits p21-induced transcription. Reverses doxorubicin -induced tumor-promoting paracrine activities in vivo .
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