SIB 1553A hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 4766
• Prices: $165.00, $685.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 191611-89-9
• Chemical Name: (±)-4-[[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio]phenolhydrochloride
• Formula: C13H19NOS.HCl
• Molecular Weight: 273.82
• Purity: >98 %
• Description: Nicotinic acetylcholine receptor (nAChR) agonist. Displays selectivity for β 4 subunit-containing receptors. Stimulates acetylcholine levels and other neurotransmitters relevant for cognitive processes. Improves attention deficits and memory performance in a Parkinson's disease model.

Product References

4-[[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A): a - 4-[[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A): a

Vernier JM, El-Abdellaoui H, Holsenback H, Cosford ND, Bleicher L, Barker G, Bontempi B, Chavez-Noriega L, Menzaghi F, Rao TS, Reid R, Sacaan AI, Suto C, Washburn M, Lloyd GK, McDonald IA. J Med Chem. 1999 May 20;42(10):1684-6.

In vitro pharmacological characterization of - In vitro pharmacological characterization of

Rao TS, Adams PB, Correa LD, Santori EM, Sacaan AI, Reid RT, Suto CM, Vernier JM. Brain Res. 2003 Aug 15;981(1-2):85-98.

The subtype-selective nicotinic acetylcholine receptor agonist SIB-1553A improves - The subtype-selective nicotinic acetylcholine receptor agonist SIB-1553A improves

Schneider JS, Tinker JP, Menzaghi F, Lloyd GK. J Pharmacol Exp Ther. 2003 Jul;306(1):401-6. Epub 2003 Apr 29.