Sibutramine hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 1214
• Prices: $115.00, $485.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 84485-00-7
• Chemical Name: 1-(4-Chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)cyclobutanemethanaminehydrochloride
• Formula: C17H26NCl.HCl
• Molecular Weight: 316.31
• Purity: >99 %
• Description: 5-HT and noradrenalin re-uptake inhibitor (SNRI). Produces weight loss in rats via inhibition of food intake and increased energy expenditure. Antidepressant.

Product References

In vivo criteria to differentiate monoamine reuptake inhibitors from releasing - In vivo criteria to differentiate monoamine reuptake inhibitors from releasing

Gundlah C, Martin KF, Heal DJ, Auerbach SB. J Pharmacol Exp Ther. 1997 Nov;283(2):581-91.

Comparison of the effects of sibutramine and other monoamine reuptake inhibitors - Comparison of the effects of sibutramine and other monoamine reuptake inhibitors

Jackson HC, Needham AM, Hutchins LJ, Mazurkiewicz SE, Heal DJ. Br J Pharmacol. 1997 Aug;121(8):1758-62.