SKF 82958 hydrobromide

• Supplier: Tocris Bioscience
• Catalog: 1447
• Prices: $135.00, $579.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 74115-01-8
• Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-1H-3-benzazepine-7,8-diolhydrobromide
• Formula: C19H20ClNO2.HBr
• Molecular Weight: 410.73
• Purity: >98 %
• Description: D 1 agonist. Increases renal blood flow in animal models and promotes contralateral rotation in rats with unilateral lesions of the substantia nigra. Also augments GABA B inhibitory post-synaptic potentials (ipsp) in ventral tegmental area in brain slices.

Product References

SCH 23390 and SK&F 83566 are antagonists at vascular dopamine and serotonin - SCH 23390 and SK&F 83566 are antagonists at vascular dopamine and serotonin

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Effects of dopamine D1 antagonists SCH23390 and SK&F83566 on locomotor activities - Effects of dopamine D1 antagonists SCH23390 and SK&F83566 on locomotor activities

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Locomotor stereotypy produced by dexbenzetimide and scopolamine is reduced by SKF - Locomotor stereotypy produced by dexbenzetimide and scopolamine is reduced by SKF

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Development of a high-throughput screening paradigm for the discovery of - Development of a high-throughput screening paradigm for the discovery of

Conley JM, Brand CS, Bogard AS, Pratt EP, Xu R, Hockerman GH, Ostrom RS, Dessauer CW, Watts VJ. J Pharmacol Exp Ther. 2013 Nov;347(2):276-87.