| Name | SKF 86466 hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2008 |
| Prices | $159.00, $665.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 86129-54-6 |
| Chemical Name | 6-Chloro-N-methyl-2,3,4,5-tetrahydro-1-H-3-benzazepinehydrochloride |
| Formula | C11H14ClN.HCl |
| Molecular Weight | 232.15 |
| Purity | >98 % |
| Description | Potent and selective α 2 antagonist at pre- and post-junctional α 2 -adrenoceptors (K i values are 13 and 17 nM respectively). Exhibits antihypertensive activity in a rat model. |
| Supplier Page | Shop |
Roesler JM, McCafferty JP, DeMarinis RM, Matthews WD, Hieble JP. J Pharmacol Exp Ther. 1986 Jan;236(1):1-7.
Schafers RF, Elliott HL, Howie CA, Reid JL. Br J Clin Pharmacol. 1990 Dec;30(6):884-8.