SKF 91488 dihydrochloride

• Supplier: Tocris Bioscience
• Catalog: 1081
• Prices: $99.00, $419.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 68941-21-9
• Chemical Name: 4-(N,N-Dimethylamino)butylisothioureadihydrochloride
• Formula: C7H17N3S.2HCl
• Molecular Weight: 248.21
• Description: Homolog of dimaprit (Cat. No. 0506); strong inhibitor of histamine N-methyltransferase. Exhibits no histamine agonist activity.

Product References

New inhibitors of histamine-N-methyltransferase. - New inhibitors of histamine-N-methyltransferase.

Beaven MA, Shaff RE. Biochem Pharmacol. 1979;28(2):183-8.

Inhibition of histamine methylation in vivo by the dimaprit analog, SKF Compound - Inhibition of histamine methylation in vivo by the dimaprit analog, SKF Compound

Beaven MA, Shaff RE. Agents Actions. 1979 Dec;9(5-6):455-60.

Histamine N-methyltransferase controls the contractile response of guinea pig - Histamine N-methyltransferase controls the contractile response of guinea pig

Ohrui T, Yamauchi K, Sekizawa K, Ohkawara Y, Maeyama K, Sasaki M, Takemura M, Wada H, Watanabe T, Sasaki H, et al.. J Pharmacol Exp Ther. 1992 Jun;261(3):1268-72.

Effects of two histamine-N-methyltransferase inhibitors, SKF 91488 and BW 301 U, - Effects of two histamine-N-methyltransferase inhibitors, SKF 91488 and BW 301 U,

Malmberg-Aiello P, Lamberti C, Ipponi A, Hanninen J, Ghelardini C, Bartolini A. Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar;355(3):354-60.