| Name | SMANT hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 0751 |
| Prices | $139.00, $585.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1177600-74-6 |
| Chemical Name | N-(4-Bromophenyl)-3,5-dimethyl-1-piperidinepropanamidehydrochloride |
| Formula | C16H23BrN2O.HCl |
| Molecular Weight | 375.73 |
| Purity | >99 % |
| Description | Inhibitor of Smoothened (Smo) signaling via a unique mechanism. Inhibits Shh-induced accumulation of Smo::EGFP fusion protein in the primary cilium (IC 50 = 1.1 μ M). Inhibits both wild-type Smo and an oncogenic form (SmoM2) with similar efficacy. |
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