SMER 3

• Supplier: Tocris Bioscience
• Catalog: 4297
• Prices: $175.00, $709.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 67200-34-4
• Chemical Name: 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
• Formula: C11H4N4O2
• Molecular Weight: 224.18
• Purity: >98 %
• Description: Selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCF Met30 ) in vitro and in vivo . Induces the expression of MET genes; blocks cell proliferation. Enhancer of rapamycin (Cat. No. 1292).

Product References

Chemical genetics screen for enhancers of rapamycin identifies a specific - Chemical genetics screen for enhancers of rapamycin identifies a specific

Aghajan M, Jonai N, Flick K, Fu F, Luo M, Cai X, Ouni I, Pierce N, Tang X, Lomenick B, Damoiseaux R, Hao R, Del Moral PM, Verma R, Li Y, Li C, Houk KN, Jung ME, Zheng N, Huang L, Deshaies RJ, Kaiser P, Huang J. Nat Biotechnol. 2010 Jul;28(7):738-42.