Sodium butyrate

• Supplier: Tocris Bioscience
• Catalog: 3152
• Prices: $59.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 156-54-7
• Chemical Name: Butanoicacidsodiumsalt
• Formula: C4H7NaO2
• Molecular Weight: 110.09
• Description: Histone deacetylase inhibitor. Restores contextual memory in a transgenic mouse model of Alzheimer's disease. Shown to induce pancreatic progenitor formation. Directs the differentiation of mouse embryonic stem cells into hepatocytes when used in combination with the cytokine Activin A. Also augments transcription factor stimulated iPSC generation.

Product References

Suppression of histone deacetylation in vivo and in vitro by sodium butyrate. - Suppression of histone deacetylation in vivo and in vitro by sodium butyrate.

Boffa LC, Vidali G, Mann RS, Allfrey VG. J Biol Chem. 1978 May 25;253(10):3364-6.

Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in - Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in

Kilgore M, Miller CA, Fass DM, Hennig KM, Haggarty SJ, Sweatt JD, Rumbaugh G. Neuropsychopharmacology. 2010 Mar;35(4):870-80.

Effects of sodium butyrate on the differentiation of pancreatic and hepatic - Effects of sodium butyrate on the differentiation of pancreatic and hepatic

Ren M, Yan L, Shang CZ, Cao J, Lu LH, Min J, Cheng H. J Cell Biochem. 2010 Jan 1;109(1):236-44.

Differentiation of mouse embryonic stem cells into hepatocytes induced by a - Differentiation of mouse embryonic stem cells into hepatocytes induced by a

Zhou M, Li P, Tan L, Qu S, Ying QL, Song H. J Cell Biochem. 2010 Feb 15;109(3):606-14.