Name | SP 141 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 5309 |
Prices | $185.00, $755.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 1253491-42-7 |
Chemical Name | 6-Methoxy-1-(1-naphthalenyl)-9H-pyrido[3,4-b]indole |
Formula | C22H16N2O |
Molecular Weight | 324.38 |
Purity | >98 % |
Description | High affinity MDM2 inhibitor (K i = 28 nM); directly binds MDM2. Inhibits MDM2 expression and induces MDM2 autoubiquitination and proteasomal degradation. Attenuates growth of breast cancer xenograft tumors. Cell permeable. |
Supplier Page | Shop |