SP 141

Name SP 141
Supplier Tocris Bioscience
Catalog 5309
Prices $185.00, $755.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 1253491-42-7
Chemical Name 6-Methoxy-1-(1-naphthalenyl)-9H-pyrido[3,4-b]indole
Formula C22H16N2O
Molecular Weight 324.38
Purity >98 %
Description High affinity MDM2 inhibitor (K i = 28 nM); directly binds MDM2. Inhibits MDM2 expression and induces MDM2 autoubiquitination and proteasomal degradation. Attenuates growth of breast cancer xenograft tumors. Cell permeable.
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