Spermine NONOate

• Supplier: Tocris Bioscience
• Catalog: 0958
• Prices: $89.00, $375.00
• Sizes: 10 mg, 50 mg
• Cas Number: 136587-13-8
• Chemical Name: N-[4-[1-(3-Aminopropyl)-2-hydroxy-2-nitrosohydrazino]butyl-1,3-propanediamine
• Formula: C10H26N6O2
• Molecular Weight: 262.35
• Description: A stable complex of nitric oxide and spermine used to generate a controlled release of nitric oxide in solution (EC 50 = 6.2 μ M for relaxation of rabbit aorta, and t ½ =39 min at 37°C, pH 7.4, aqueous solution).

Product References

Complexes of .NO with nucleophiles as agents for the controlled biological - Complexes of .NO with nucleophiles as agents for the controlled biological

Maragos CM, Morley D, Wink DA, Dunams TM, Saavedra JE, Hoffman A, Bove AA, Isaac L, Hrabie JA, Keefer LK. J Med Chem. 1991 Nov;34(11):3242-7.

Measurement and modeling of nitric oxide release rates for nitric oxide donors. - Measurement and modeling of nitric oxide release rates for nitric oxide donors.

Ramamurthi A, Lewis RS. Chem Res Toxicol. 1997 Apr;10(4):408-13.

In vitro comparison of two NONOates (novel nitric oxide donors) on rat pulmonary - In vitro comparison of two NONOates (novel nitric oxide donors) on rat pulmonary

Homer K, Wanstall J. Eur J Pharmacol. 1998 Aug 28;356(1):49-57.

Comparative effects of several nitric oxide donors on intracellular cyclic GMP - Comparative effects of several nitric oxide donors on intracellular cyclic GMP

Ferrero R, Rodriguez-Pascual F, Miras-Portugal MT, Torres M. Br J Pharmacol. 1999 Jun;127(3):779-87.