Spexin

Name Spexin
Supplier Tocris Bioscience
Catalog 1135
Prices $205.00
Sizes 1 mg
Function Type Agonist
Cas Number 1370290-58-6
Formula C74H114N20O19S
Molecular Weight 1619.9
Description Potent galanin receptor 2/3 (GAL 2 /GAL 3 ) agonist (EC 50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Attenuates LH secretion in goldfish. Exhibits anxiolytic effects in vivo .
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Product References

Structural requirements for long-chain (sphingoid) base inhibition of protein - Structural requirements for long-chain (sphingoid) base inhibition of protein

Merrill AH Jr, Nimkar S, Menaldino D, Hannun YA, Loomis C, Bell RM, Tyagi SR, Lambeth JD, Stevens VL, Hunter R, et al.. Biochemistry. 1989 Apr 18;28(8):3138-45.

Sphingosine inhibition and promotion of histamine release from isolated rat mast - Sphingosine inhibition and promotion of histamine release from isolated rat mast

Grosman N. Agents Actions. 1990 Nov;31(3-4):171-67.