Spiroxatrine

• Supplier: Tocris Bioscience
• Catalog: 2968
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 1054-88-2
• Chemical Name: 8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one
• Formula: C22H25N3O3
• Molecular Weight: 379.46
• Description: 5-HT 1A antagonist. More active and selective than spiperone. Also a very potent α 2C adrenergic receptor antagonist.

Product References

Spiroxatrine: a selective serotonin1A receptor antagonist. - Spiroxatrine: a selective serotonin1A receptor antagonist.

Nelson DL, Taylor EW. Eur J Pharmacol. 1986 May 13;124(1-2):207-8.

Centrally acting hypotensive agents with affinity for 5-HT1A binding sites - Centrally acting hypotensive agents with affinity for 5-HT1A binding sites

Schoeffter P, Hoyer D. Br J Pharmacol. 1988 Nov;95(3):975-85.

Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of - Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of

Bylund DB, Blaxall HS, Iversen LJ, Caron MG, Lefkowitz RJ, Lomasney JW. Mol Pharmacol. 1992 Jul;42(1):1-5.