SR 12813

Name SR 12813
Supplier Tocris Bioscience
Catalog 2476
Prices $109.00, $455.00
Sizes 10 mg, 50 mg
Function Type Agonist
Cas Number 126411-39-0
Chemical Name [[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonicacidtetraethylester
Formula C24H42O7P2
Molecular Weight 504.53
Purity >99 %
Description Pregnane X receptor (PXR) agonist (EC 50 values are 200 and 700 nM for human and rabbit PXR respectively). Activates the farnesoid X receptor (FXR) at μ M concentrations. Displays hypocholesterolaemic activity via enchanced degradation of HMG-CoA reductase.
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