| Name | SR 144528 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2309 |
| Prices | $189.00, $765.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 192703-06-3 |
| Chemical Name | 5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide |
| Formula | C29H34ClN3O |
| Molecular Weight | 476.05 |
| Purity | >98 % |
| Description | High affinity and selective CB 2 inverse agonist (K i = 0.6 nM). Exhibits >700-fold selectivity for CB 2 over CB 1 receptors. Blocks the effects of CP 55,940 (Cat. No. 0949) on forskolin-sensitive adenylyl cyclase activity and MAPK in CHO cells expressing CB 2 receptors. Also blocks CP 55,940-induced B-cell activation. Orally bioavailable. |
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