Name | SR 2211 |
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Supplier | Tocris Bioscience |
Catalog | 2022 |
Prices | $195.00, $805.00 |
Sizes | 10 mg, 50 mg |
Function Type | Agonist |
Cas Number | 1359164-11-6 |
Chemical Name | 2-Fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-a,a-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol |
Formula | C26H24F7N3O |
Molecular Weight | 527.48 |
Purity | >98 % |
Description | Selective inverse agonist of retinoic acid receptor-related orphan receptor γ (ROR γ ) (K i = 105 nM; IC 50 ~320 nM). Exhibits weak activity at liver X receptor α (LXR α ); does not affect the transcriptional activity of farnesoid X receptors (FXR), and has no impact on the transcriptional activity of ROR α . |
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