SR 58611A hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 1205
• Prices: $185.00, $755.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 121524-09-2
• Chemical Name: [[(7S)-7-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydro-2-naphthalenyl]ox]yaceticacidethylesterhydrochloride
• Formula: C22H26ClNO4.HCl
• Molecular Weight: 440.36
• Purity: >98 %
• Description: Selective β 3-adrenergic receptor agonist. Displays both anxiolytic and antidepressant effects in rodent models. Orally active and brain penetrant.

Product References

Behavioral effects of the beta3 adrenoceptor agonist SR58611A: is it the putative - Behavioral effects of the beta3 adrenoceptor agonist SR58611A: is it the putative

Consoli D, Leggio GM, Mazzola C, Micale V, Drago F. Eur J Pharmacol. 2007 Nov 14;573(1-3):139-47. Epub 2007 Jul 4.

Effects of the beta3-adrenoceptor (Adrb3) agonist SR58611A (amibegron) on - Effects of the beta3-adrenoceptor (Adrb3) agonist SR58611A (amibegron) on

Claustre Y, Leonetti M, Santucci V, Bougault I, Desvignes C, Rouquier L, Aubin N, Keane P, Busch S, Chen Y, Palejwala V, Tocci M, Yamdagni P, Didier M, Avenet P, Le Fur G, Oury-Donat F, Scatton B, Steinberg R. Neuroscience. 2008 Oct 2;156(2):353-64.

Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety - Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety

Stemmelin J, Cohen C, Terranova JP, Lopez-Grancha M, Pichat P, Bergis O, Decobert M, Santucci V, Francon D, Alonso R, Stahl SM, Keane P, Avenet P, Scatton B, le Fur G, Griebel G. Neuropsychopharmacology. 2008 Feb;33(3):574-87. Epub 2007 Apr 25.

The beta3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced - The beta3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced

Tamburella A, Micale V, Leggio GM, Drago F. Eur Neuropsychopharmacol. 2010 Oct;20(10):704-13. doi: