SR 7826

Name SR 7826
Supplier Tocris Bioscience
Catalog 1511
Prices $195.00, $805.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 1219728-20-7
Chemical Name N-(2-Hydroxyethyl)-N'-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea
Formula C22H21N5O2
Molecular Weight 387.43
Purity >98 %
Description Potent and selective LIMK inhibitor (IC 50 values are 43, 5536 and 6565 nM for LIMK1, ROCKI and ROCKII, respectively). Inhibits cofilin phosphorylation in A7r5 cells and suppresses migration and invasion of PC-3 cells in vitro . Orally bioavailable.
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